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NEWS AND EVENTS

RTK GROUP ANNOUNCES INVESTMENT IN UNRAVEL BIOSCIENCES

June 14, 2022

An early-stage advisory and investment fund supporting emerging technologies in the biotech and pharmaceutical sector, today announced its participation in seed-round capital funding of Unravel Biosciences, Inc. ("Unravel"). The financial terms of the transaction were not disclosed.

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Scilex Holding Company, a Sorrento Company, enters into an agreement for an exclusive license with ROMEG Therapeutics, LLC, for the right to commercialize Gloperba®, an FDA-approved prophylactic treatment for painful gout flares in adults, in the US.

June 14, 2022

Scilex Holding Company has entered into a license and commercialization agreement with ROMEG Therapeutics for the exclusive right to market and distribute Gloperba, an oral solution for adults suffering from gout, in the US

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Unravel Biosciences Partners with TMA Precision Health to Advance Drug Treatment for Rett Syndrome into the Clinic

July 5, 2022

Unravel Biosciences today announced a partnership with TMA Precision Health aimed at identifying rare Rett Syndrome patients for inclusion in Unravel's first-in-human reformulated drug trial.

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Unravel Biosciences Announces Submission of RVL-001 Clinical Study Applications for Rett Syndrome and Pitt Hopkins Syndrome to Colombian Health Regulatory Authority

April 29, 2025

Submissions follow Ethics Committee Approvals for Both Studies Received Earlier This Month and Have Been Accepted for INVIMA Priority Review Under Fast Track Program for Rare Disease

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Unravel Biosciences and COMBINED Brain Announce Large-Scale Drug Discovery Collaboration for Rare Neurological Diseases with High Unmet Need

February 27, 2025

The agreement represents one of the largest biopharma-patient community partnerships of its kind and will accelerate the identification of potential drug candidates across multiple ultra-rare diseases.

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Scilex Holding Company Amends its License Agreement with Romeg Therapeutics, LLC, For the Worldwide Rights to Commercialize Gloperba®, an FDA-Approved Prophylactic Treatment for Painful Gout Flares in Adults

January 16, 2025

PALO ALTO, Calif., Jan. 16, 2025 (GLOBE NEWSWIRE) -- Scilex Holding Company (Nasdaq: SCLX, “Scilex” or “Company”), an innovative revenue-generating company

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Unravel Biosciences and PECET Announce Collaboration to Conduct Clinical Trials of RVL-001 in Rett Syndrome and Pitt Hopkins Syndrome in Colombia

October 24, 2024

Study site selection and finalization of clinical trial agreement final step toward initiation of RVL-001 proof-of-concept clinical studies early next year

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Scilex Holding Company Announces FDA Final Approval to Precision Dosing for GLOPERBA® Label

August 29, 2024

PALO ALTO, Calif., Aug. 29, 2024 (GLOBE NEWSWIRE) -- Scilex Holding Company (Nasdaq: SCLX, “Scilex” or the “Company”), an innovative revenue-generating company focused on acquiring

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Scilex Holding Company announces the U.S. FDA has approved the sNDA for commercial manufacturing of Gloperba® which will be launched in the US in the week of June 10th 2024

June 6, 2024

PALO ALTO, Calif., June 06, 2024 (GLOBE NEWSWIRE) -- Scilex Holding Company (Nasdaq: SCLX, “Scilex” or “Company”), an innovative revenue-generating

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Unravel Biosciences Receives FDA Orphan Drug Designation for Vorinostat (RVL-001) as a Treatment for Rett Syndrome

May 28, 2024

Initiation of global clinical development program for RVL-001 in Rett syndrome underway, with recently announced Rett studies in the US led by Vanderbilt and in Colombia led by Unravel.

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Scilex Holding Company Announces Seeking Approval from the FDA for Modification of the Gloperba® Label to Provide Specific Dosing Guidance for Patients with Renal Impairment and Other Circumstances Where Dose Adjustment is Needed

March 20, 2024

Seek approval from the FDA for the modification of the Gloperba® label to include its ability to utilize dosing flexibility of liquid formulation

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Scilex Holding Company announces completion of commercial manufacturing of Gloperba® with the brand marketed and distributed under Scilex Pharmaceuticals, Inc. and is expecting to Launch in the U.S. in the first quarter of 2024

November 27, 2023

ALO ALTO, Calif., Nov. 27, 2023 (GLOBE NEWSWIRE) -- Scilex Holding Company (Nasdaq: SCLX, “Scilex” or “Company”)

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UNRAVEL BIOSCIENCES ANNOUNCES POSITIVE FEEDBACK FROM FDA PRE-IND MEETING ON RVL001 RETT SYNDROME PROGRAM

May 15, 2023

FDA pre-IND feedback provides a clear path forward to initiate proof-of-concept clinical study in Rett Syndrome patients later this year

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RTK GROUP JOINS THE MASSACHUSETTS BIOTECHNOLOGY COUNCIL

January 31, 2023

Membership with MassBio expected to enhance RTK Group's mission to support advancing the development of promising technology to improve patient lives.

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by enabling them to develop promising technologies and reach their potential to benefit patients.

We have one goal: to enable better patient lives and a better world through better healthcare. We take great satisfaction in partnering with companies having high potential to disrupt the healthcare ecosystem and helping support high‐performing management teams to realize their goals.

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